Role of Dll4 / Notch in the formation and wiring of the lymphatic network in zebrafish

OBJECTIVES: In zebrafish embryos, sprouts from the axial vein have lymphangiogenic potential, as they give rise to the first lymphatics. Here, we studied whether Notch signaling, which regulates cell fate decisions and vessel morphogenesis, controls lymphatic development. METHODS AND RESULTS: Knockd...

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Dades bibliogràfiques
Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Geudens, Ilse, Herpers, Robert, Hermans, Karlien, Segura, Inmaculada, de Almodovar, Carmen Ruiz, Bussmann, Jeroen, De Smet, Frederik, Vandevelde, Wouter, Hogan, Benjamin M, Siekmann, Arndt, Claes, Filip, Moore, John C, Pistocchi, Anna Silvia, Loges, Sonja, Mazzone, Massimiliano, Mariggi, Giovanni, Bruyère, Françoise, Cotelli, Franco, Kerjaschki, Dontscho, Noël, Agnes, Foidart, Jean-Michel, Gerhardt, Holger, Ny, Annelii, Langenberg, Tobias, Lawson, Nathan D, Duckers, Henricus J, Schulte-Merker, Stefan, Carmeliet, Peter, Dewerchin, Mieke
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497575/
https://ncbi.nlm.nih.gov/pubmed/20466977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.203034
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