Role of Dll4 / Notch in the formation and wiring of the lymphatic network in zebrafish

OBJECTIVES: In zebrafish embryos, sprouts from the axial vein have lymphangiogenic potential, as they give rise to the first lymphatics. Here, we studied whether Notch signaling, which regulates cell fate decisions and vessel morphogenesis, controls lymphatic development. METHODS AND RESULTS: Knockd...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Geudens, Ilse, Herpers, Robert, Hermans, Karlien, Segura, Inmaculada, de Almodovar, Carmen Ruiz, Bussmann, Jeroen, De Smet, Frederik, Vandevelde, Wouter, Hogan, Benjamin M, Siekmann, Arndt, Claes, Filip, Moore, John C, Pistocchi, Anna Silvia, Loges, Sonja, Mazzone, Massimiliano, Mariggi, Giovanni, Bruyère, Françoise, Cotelli, Franco, Kerjaschki, Dontscho, Noël, Agnes, Foidart, Jean-Michel, Gerhardt, Holger, Ny, Annelii, Langenberg, Tobias, Lawson, Nathan D, Duckers, Henricus J, Schulte-Merker, Stefan, Carmeliet, Peter, Dewerchin, Mieke
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497575/
https://ncbi.nlm.nih.gov/pubmed/20466977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.203034
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