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Pharmacodynamic effects of daclizumab in the intrathecal compartment

OBJECTIVE: It was previously demonstrated that daclizumab therapy normalizes cellular cerebrospinal fluid (CSF) abnormalities typical of multiple sclerosis (MS) in the majority of treated patients. However, CSF cells represent only the mobile portion of intrathecal immune responses. Therefore, we as...

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Détails bibliographiques
Publié dans:Ann Clin Transl Neurol
Auteurs principaux: Komori, Mika, Kosa, Peter, Stein, Jason, Zhao, Vivian, Blake, Andrew, Cherup, Jamie, Sheridan, James, Wu, Tianxia, Bielekova, Bibiana
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497534/
https://ncbi.nlm.nih.gov/pubmed/28695148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.427
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