Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis

OBJECTIVE: Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus plac...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Komori, Mika, Lin, Yen Chih, Cortese, Irene, Blake, Andrew, Ohayon, Joan, Cherup, Jamie, Maric, Dragan, Kosa, Peter, Wu, Tianxia, Bielekova, Bibiana
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774261/
https://ncbi.nlm.nih.gov/pubmed/27042677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.293
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