Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis

OBJECTIVE: Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus plac...

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Опубликовано в: :Ann Clin Transl Neurol
Главные авторы: Komori, Mika, Lin, Yen Chih, Cortese, Irene, Blake, Andrew, Ohayon, Joan, Cherup, Jamie, Maric, Dragan, Kosa, Peter, Wu, Tianxia, Bielekova, Bibiana
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774261/
https://ncbi.nlm.nih.gov/pubmed/27042677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.293
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