Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis

OBJECTIVE: Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus plac...

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Bibliographic Details
Published in:Ann Clin Transl Neurol
Main Authors: Komori, Mika, Lin, Yen Chih, Cortese, Irene, Blake, Andrew, Ohayon, Joan, Cherup, Jamie, Maric, Dragan, Kosa, Peter, Wu, Tianxia, Bielekova, Bibiana
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774261/
https://ncbi.nlm.nih.gov/pubmed/27042677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.293
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