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Daclizumab reverses intrathecal immune cell abnormalities in multiple sclerosis

OBJECTIVE: Novel treatments such as natalizumab and fingolimod achieve their therapeutic efficacy in multiple sclerosis (MS) by blocking access of subsets of immune cells into the central nervous system, thus creating nonphysiological intrathecal immunity. In contrast, daclizumab, a humanized monocl...

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Библиографические подробности
Опубликовано в: :Ann Clin Transl Neurol
Главные авторы: Lin, Yen Chih, Winokur, Paige, Blake, Andrew, Wu, Tianxia, Romm, Elena, Bielekova, Bibiana
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435700/
https://ncbi.nlm.nih.gov/pubmed/26000318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.181
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