Pharmacodynamic effects of daclizumab in the intrathecal compartment

OBJECTIVE: It was previously demonstrated that daclizumab therapy normalizes cellular cerebrospinal fluid (CSF) abnormalities typical of multiple sclerosis (MS) in the majority of treated patients. However, CSF cells represent only the mobile portion of intrathecal immune responses. Therefore, we as...

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Veröffentlicht in:Ann Clin Transl Neurol
Hauptverfasser: Komori, Mika, Kosa, Peter, Stein, Jason, Zhao, Vivian, Blake, Andrew, Cherup, Jamie, Sheridan, James, Wu, Tianxia, Bielekova, Bibiana
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497534/
https://ncbi.nlm.nih.gov/pubmed/28695148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.427
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