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Menthol Decreases Oral Nicotine Aversion in C57BL/6 Mice Through a TRPM8-Dependent Mechanism

BACKGROUND: Nicotine is a major oral irritant in smokeless tobacco products and has an aversive taste. Mentholated smokeless tobacco products are highly popular, suggesting that menthol increases their palatability and may facilitate initiation of product use. While menthol is known to reduce respir...

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Détails bibliographiques
Publié dans:Tob Control
Auteurs principaux: Fan, Lu, Balakrishna, Shrilatha, Jabba, Sairam V., Bonner, Pamela E., Taylor, Seth R., Picciotto, Marina R., Jordt, Sven-Eric
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496986/
https://ncbi.nlm.nih.gov/pubmed/27698211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/tobaccocontrol-2016-053209
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