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Menthol Decreases Oral Nicotine Aversion in C57BL/6 Mice Through a TRPM8-Dependent Mechanism

BACKGROUND: Nicotine is a major oral irritant in smokeless tobacco products and has an aversive taste. Mentholated smokeless tobacco products are highly popular, suggesting that menthol increases their palatability and may facilitate initiation of product use. While menthol is known to reduce respir...

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Detalhes bibliográficos
Publicado no:Tob Control
Main Authors: Fan, Lu, Balakrishna, Shrilatha, Jabba, Sairam V., Bonner, Pamela E., Taylor, Seth R., Picciotto, Marina R., Jordt, Sven-Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496986/
https://ncbi.nlm.nih.gov/pubmed/27698211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/tobaccocontrol-2016-053209
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