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TRPM8 is the Principal Mediator of Menthol-induced Analgesia of Acute and Inflammatory Pain

Menthol, the cooling natural product of peppermint, is widely used in medicinal preparations for the relief of acute and inflammatory pain in sports injuries, arthritis and other painful conditions. Menthol induces the sensation of cooling by activating TRPM8, an ion channel in cold-sensitive periph...

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Bibliographic Details
Main Authors: Liu, Boyi, Fan, Lu, Balakrishna, Shrilatha, Sui, Aiwei, Morris, John B., Jordt, Sven-Eric
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778045/
https://ncbi.nlm.nih.gov/pubmed/23820004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.06.043
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