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Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood

High temperature requirement factor A3 (HtrA3), a member of the HtrA protease family, is highly expressed in the developing placenta, including the maternal decidual cells in both mice and humans. In this study we deleted the HtrA3 gene in the mouse and crossed females carrying zero, one, or two Htr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Ying, Salamonsen, Lois A., Hyett, Jonathan, Costa, Fabricio da Silva, Nie, Guiying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496872/
https://ncbi.nlm.nih.gov/pubmed/28676687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04867-3
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