Transethnic genome-wide scan identifies novel Alzheimer disease loci

BACKGROUND: Genetic loci for Alzheimer disease (AD) have been identified in whites of European ancestry, but the genetic architecture of AD among other populations is less understood. METHODS: We conducted a transethnic genome-wide association study (GWAS) for late-onset AD in Stage 1 sample includi...

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Pubblicato in:Alzheimers Dement
Autori principali: Jun, Gyungah R., Chung, Jaeyoon, Mez, Jesse, Barber, Robert, Beecham, Gary W., Bennett, David A., Buxbaum, Joseph D., Byrd, Goldie S., Carrasquillo, Minerva M., Crane, Paul K., Cruchaga, Carlos, De Jager, Philip, Ertekin-Taner, Nilufer, Evans, Denis, Fallin, M. Danielle, Foroud, Tatiana M., Friedland, Robert P., Goate, Alison M., Graff-Radford, Neill R., Hendrie, Hugh, Hall, Kathleen S., Hamilton-Nelson, Kara L., Inzelberg, Rivka, Kamboh, M. Ilyas, Kauwe, John SK, Kukull, Walter A., Kunkle, Brian W., Kuwano, Ryozo, Larson, Eric B., Logue, Mark W., Manly, Jennifer J., Martin, Eden R., Montine, Thomas J., Mukherjee, Shubhabrata, Naj, Adam, Reiman, Eric M., Reitz, Christiane, Sherva, Richard, George-Hyslop, Peter H., Thornton, Timothy, Younkin, Steven G., Vardarajan, Badri N., Wang, Li-San, Wendlund, Jens R., Winslow, Ashley R., Haines, Jonathan, Mayeux, Richard, Pericak-Vance, Margaret A., Schellenberg, Gerard, Lunetta, Kathryn L., Farrer, Lindsay A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496797/
https://ncbi.nlm.nih.gov/pubmed/28183528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.12.012
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