STXBP4 drives tumor growth and is associated with poor prognosis through PDGF Receptor signaling in lung squamous cell carcinoma

PURPOSE: Expression of the ΔN isoform of p63 (ΔNp63) is a diagnostic marker highly specific for lung squamous cell carcinoma (SCC). We previously found that Syntaxin Binding Protein 4 (STXBP4) regulates ΔNp63 ubiquitination, suggesting that STXBP4 may also be a SCC biomarker. To address this issue,...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Otaka, Yukihiro, Rokudai, Susumu, Kaira, Kyoichi, Fujieda, Michiru, Horikoshi, Ikuko, Iwakawa-Kawabata, Reika, Yoshiyama, Shinji, Yokobori, Takehiko, Ohtaki, Yoichi, Shimizu, Kimihiro, Oyama, Tetsunari, Tamura, Jun’ichi, Prives, Carol, Nishiyama, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496791/
https://ncbi.nlm.nih.gov/pubmed/28087642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1815
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