AKT3 Is a Novel Regulator of Cancer-Associated Fibroblasts in Head and Neck Squamous Cell Carcinoma

SIMPLE SUMMARY: Cancer-associated fibroblasts (CAFs) promote epithelial-to-mesenchymal transition, angiogenesis, and immunosuppression, resulting in tumor progression. The PI3K-AKT pathway is known to play vital roles in various cellular activities, including proliferation, growth, metabolism, and s...

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Publicado en:Cancers (Basel)
Autores principales: Takahashi, Hideyuki, Rokudai, Susumu, Kawabata-Iwakawa, Reika, Sakakura, Koichi, Oyama, Tetsunari, Nishiyama, Masahiko, Chikamatsu, Kazuaki
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998536/
https://ncbi.nlm.nih.gov/pubmed/33799788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061233
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