Oral administration of the nitroxide radical TEMPOL exhibits immunomodulatory and therapeutic properties in multiple sclerosis models

Therapies with both immunomodulatory and neuroprotective properties are thought to have the greatest promise in reducing the severity and progression of multiple sclerosis (MS). Several reactive oxygen (ROS) and reactive nitrogen species (RNS) are implicated in inflammatory-mediated damage to the ce...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Neil, Sarah, Huh, Jaebong, Baronas, Victoria, Li, Xinhui, McFarland, Henry F., Cherukuri, Murali, Mitchell, James B., Quandt, Jacqueline A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496657/
https://ncbi.nlm.nih.gov/pubmed/28238951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.02.018
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