Myelin Basic Protein-Specific TCR/HLA-DRB5*01:01Transgenic Mice Support the Etiologic Role of DRB5*01:01 in Multiple Sclerosis ()

Genetic susceptibility to multiple sclerosis (MS) has been linked to the HLA-DR15 haplotype consisting of DRB1*15:01(DR2b)- and DRB5*01:01(DR2a) alleles. Given almost complete linkage disequilibrium of the two alleles, recent studies have suggested differential roles in susceptibility (DR2b) or prot...

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Detalhes bibliográficos
Main Authors: Quandt, Jacqueline A., Huh, Jaebong, Baig, Mirza, Yao, Karen, Ito, Naoko, Bryant, Mark, Kawamura, Kazuyuki, Pinilla, Clemencia, McFarland, Henry F., Martin, Roland, Ito, Kouichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436970/
https://ncbi.nlm.nih.gov/pubmed/22888134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103087
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