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Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides

Nitroxides can undergo one- or two-electron reduction reactions to hydroxylamines or oxammonium cations, respectively, which themselves are interconvertible, thereby providing redox metabolic actions. 4-Hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (tempol) is the most extensively studied nitroxide....

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Detalhes bibliográficos
Main Authors: WILCOX, CHRISTOPHER S., PEARLMAN, ADAM
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739999/
https://ncbi.nlm.nih.gov/pubmed/19112152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.108.000240
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