Rab2 promotes autophagic and endocytic lysosomal degradation

Rab7 promotes fusion of autophagosomes and late endosomes with lysosomes in yeast and metazoan cells, acting together with its effector, the tethering complex HOPS. Here we show that another small GTPase, Rab2, is also required for autophagosome and endosome maturation and proper lysosome function i...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Lőrincz, Péter, Tóth, Sarolta, Benkő, Péter, Lakatos, Zsolt, Boda, Attila, Glatz, Gábor, Zobel, Martina, Bisi, Sara, Hegedűs, Krisztina, Takáts, Szabolcs, Scita, Giorgio, Juhász, Gábor
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496615/
https://ncbi.nlm.nih.gov/pubmed/28483915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611027
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