Rab2 promotes autophagic and endocytic lysosomal degradation

Rab7 promotes fusion of autophagosomes and late endosomes with lysosomes in yeast and metazoan cells, acting together with its effector, the tethering complex HOPS. Here we show that another small GTPase, Rab2, is also required for autophagosome and endosome maturation and proper lysosome function i...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Lőrincz, Péter, Tóth, Sarolta, Benkő, Péter, Lakatos, Zsolt, Boda, Attila, Glatz, Gábor, Zobel, Martina, Bisi, Sara, Hegedűs, Krisztina, Takáts, Szabolcs, Scita, Giorgio, Juhász, Gábor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2017
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496615/
https://ncbi.nlm.nih.gov/pubmed/28483915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611027
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