Rab2 promotes autophagic and endocytic lysosomal degradation

Rab7 promotes fusion of autophagosomes and late endosomes with lysosomes in yeast and metazoan cells, acting together with its effector, the tethering complex HOPS. Here we show that another small GTPase, Rab2, is also required for autophagosome and endosome maturation and proper lysosome function i...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Lőrincz, Péter, Tóth, Sarolta, Benkő, Péter, Lakatos, Zsolt, Boda, Attila, Glatz, Gábor, Zobel, Martina, Bisi, Sara, Hegedűs, Krisztina, Takáts, Szabolcs, Scita, Giorgio, Juhász, Gábor
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496615/
https://ncbi.nlm.nih.gov/pubmed/28483915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611027
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