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Polarity of varicosity initiation in central neuron mechanosensation

Little is known about mechanical regulation of morphological and functional polarity of central neurons. In this study, we report that mechanical stress specifically induces varicosities in the axons but not the dendrites of central neurons by activating TRPV4, a Ca(2+)/Na(+)-permeable mechanosensit...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Gu, Yuanzheng, Jukkola, Peter, Wang, Qian, Esparza, Thomas, Zhao, Yi, Brody, David, Gu, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496611/
https://ncbi.nlm.nih.gov/pubmed/28606925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606065
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