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Polarity of varicosity initiation in central neuron mechanosensation

Little is known about mechanical regulation of morphological and functional polarity of central neurons. In this study, we report that mechanical stress specifically induces varicosities in the axons but not the dendrites of central neurons by activating TRPV4, a Ca(2+)/Na(+)-permeable mechanosensit...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Gu, Yuanzheng, Jukkola, Peter, Wang, Qian, Esparza, Thomas, Zhao, Yi, Brody, David, Gu, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496611/
https://ncbi.nlm.nih.gov/pubmed/28606925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606065
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