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Suppression of Inflammatory Demyelinaton and Axon Degeneration through Inhibiting Kv3 Channels

The development of neuroprotective and repair strategies for treating progressive multiple sclerosis (MS) requires new insights into axonal injury. 4-aminopyridine (4-AP), a blocker of voltage-gated K(+) (Kv) channels, is used in symptomatic treatment of progressive MS, but the underlying mechanism...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Jukkola, Peter, Gu, Yuanzheng, Lovett-Racke, Amy E., Gu, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662905/
https://ncbi.nlm.nih.gov/pubmed/29123469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00344
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