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Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?

Phenotypic plasticity, the ability of cells to reversibly alter their phenotypes in response to signals, presents a significant clinical challenge to treating solid tumors. Tumor cells utilize phenotypic plasticity to evade therapies, metastasize, and colonize distant organs. As a result, phenotypic...

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Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Jolly, Mohit Kumar, Tripathi, Satyendra C., Somarelli, Jason A., Hanash, Samir M., Levine, Herbert
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496493/
https://ncbi.nlm.nih.gov/pubmed/28548388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12084
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