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Sustained hyperosmolarity increses TGF-ß1 and Egr-1 expression in the rat renal medulla

BACKGROUND: Although TGF-ß and the transcription factor Egr-1 play an important role in both kidney fibrosis and in response to acute changes of renal medullary osmolarity, their role under sustained hypo- or hyperosmolar conditions has not been elucidated. We investigated the effects of chronic hyp...

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Bibliografske podrobnosti
izdano v:BMC Nephrol
Main Authors: Mózes, Miklós M., Szoleczky, Petra, Rosivall, László, Kökény, Gábor
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496335/
https://ncbi.nlm.nih.gov/pubmed/28673338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-017-0626-2
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