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The PPARγ agonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3
BACKGROUND: It has been proposed that peroxisome proliferator-activated receptor-γ (PPARγ) agonists might reduce renal fibrosis, however, several studies had contradictory results. Moreover, the possible interaction of TGF-β(1), PPARγ, and transcription factors in renal fibrosis have not been invest...
Sparad:
| I publikationen: | BMC Nephrol |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BioMed Central
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610924/ https://ncbi.nlm.nih.gov/pubmed/31277592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-019-1431-x |
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