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Strong epistatic and additive effects of linked candidate SNPs for Drosophila pigmentation have implications for analysis of genome-wide association studies results

BACKGROUND: The mapping resolution of genome-wide association studies (GWAS) is limited by historic recombination events and effects are often assigned to haplotype blocks rather than individual SNPs. It is not clear how many of the SNPs in the block, and which ones, are causative. Drosophila pigmen...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Gibert, Jean-Michel, Blanco, Jorge, Dolezal, Marlies, Nolte, Viola, Peronnet, Frédérique, Schlötterer, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496195/
https://ncbi.nlm.nih.gov/pubmed/28673357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1262-7
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