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Strong epistatic and additive effects of linked candidate SNPs for Drosophila pigmentation have implications for analysis of genome-wide association studies results

BACKGROUND: The mapping resolution of genome-wide association studies (GWAS) is limited by historic recombination events and effects are often assigned to haplotype blocks rather than individual SNPs. It is not clear how many of the SNPs in the block, and which ones, are causative. Drosophila pigmen...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Gibert, Jean-Michel, Blanco, Jorge, Dolezal, Marlies, Nolte, Viola, Peronnet, Frédérique, Schlötterer, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496195/
https://ncbi.nlm.nih.gov/pubmed/28673357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1262-7
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