Strong epistatic and additive effects of linked candidate SNPs for Drosophila pigmentation have implications for analysis of genome-wide association studies results

BACKGROUND: The mapping resolution of genome-wide association studies (GWAS) is limited by historic recombination events and effects are often assigned to haplotype blocks rather than individual SNPs. It is not clear how many of the SNPs in the block, and which ones, are causative. Drosophila pigmen...

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Publicado en:Genome Biol
Autores principales: Gibert, Jean-Michel, Blanco, Jorge, Dolezal, Marlies, Nolte, Viola, Peronnet, Frédérique, Schlötterer, Christian
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496195/
https://ncbi.nlm.nih.gov/pubmed/28673357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1262-7
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