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DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA
CpG-DNA and its related synthetic CpG oligodeoxynucleotides (CpG-ODNs) play an important role in immune cell survival. It has been suggested that Akt is one of the CpG-DNA-responsive serine/threonine kinases; however, the target protein of CpG-DNA that leads to Akt activation has not been elucidated...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549614/ https://ncbi.nlm.nih.gov/pubmed/15678105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600539 |
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