Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns

A glutamate-to-lysine variant (rs58542926-T) in transmembrane 6 superfamily member 2 (TM6SF2) is associated with increased fatty liver disease and diabetes in conjunction with decreased cardiovascular disease risk. To identify mediators of the effects of TM6SF2, we tested for associations between rs...

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Bibliografski detalji
Izdano u:J Lipid Res
Glavni autori: Kim, Daniel Seung, Jackson, Anne U., Li, Yatong K., Stringham, Heather M., Kuusisto, Johanna, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Burant, Charles F., Salomaa, Veikko, Boehnke, Michael, Laakso, Markku, Speliotes, Elizabeth K.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2017
Teme:
Patient-Oriented and Epidemiological Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496043/
https://ncbi.nlm.nih.gov/pubmed/28539357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P076034
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