Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats

Hepatic mitochondrial function, APOC-III, and LPL are potential targets for triglyceride (TG)-lowering drugs. After 3 weeks of dietary treatment with the compound 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA), the hepatic mitochondrial FA oxidation increased more than 5-fold in male Wistar rat...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Lindquist, Carine, Bjørndal, Bodil, Rossmann, Christine Renate, Tusubira, Deusdedit, Svardal, Asbjørn, Røsland, Gro Vatne, Tronstad, Karl Johan, Hallström, Seth, Berge, Rolf Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496034/
https://ncbi.nlm.nih.gov/pubmed/28473603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M074849
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