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Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice
Cd39 scavenges extracellular ATP and ADP, ultimately generating adenosine, a nucleoside, which has anti-inflammatory effects in the vasculature. We have evaluated the role of Cd39 in the development of atherosclerosis in hyperlipidemic mice. ApoE KO (Cd39(+/+)/ApoE(−/−)) and Cd39/ApoE double KO (DKO...
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| Publicado no: | J Lipid Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496028/ https://ncbi.nlm.nih.gov/pubmed/28487312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M072132 |
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