Hypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus.
Fanconi anemia (FA) is an inherited human disorder associated with a predisposition to cancer and characterized by anomalies in the processing of DNA cross-links and certain monoadducts. We reported previously that the frequency of psoralen-photoinduced mutations at the HPRT locus is lower in FA cel...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2236046/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8383 |
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