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Hypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus.

Fanconi anemia (FA) is an inherited human disorder associated with a predisposition to cancer and characterized by anomalies in the processing of DNA cross-links and certain monoadducts. We reported previously that the frequency of psoralen-photoinduced mutations at the HPRT locus is lower in FA cel...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Papadopoulo, D, Guillouf, C, Mohrenweiser, H, Moustacchi, E
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2236046/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8383
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