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Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts

Pulmonary fibrosis is a severe condition with no cure and limited therapeutic options. A better understanding of its pathophysiology is needed. Recent studies have suggested that pulmonary fibrosis may be driven by accelerated aging-related mechanisms. Sirtuins (SIRTs), particularly SIRT1, SIRT3, an...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Wyman, Anne E., Noor, Zahid, Fishelevich, Rita, Lockatell, Virginia, Shah, Nirav G., Todd, Nevins W., Atamas, Sergei P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495944/
https://ncbi.nlm.nih.gov/pubmed/28385812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00473.2016
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