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Contribution of two-pore K(+) channels to cardiac ventricular action potential revealed using human iPSC-derived cardiomyocytes

Two-pore K(+) (K(2p)) channels have been described in modulating background conductance as leak channels in different physiological systems. In the heart, the expression of K(2p) channels is heterogeneous with equivocation regarding their functional role. Our objective was to determine the K(2p) exp...

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Detalles Bibliográficos
Publicado en:Am J Physiol Heart Circ Physiol
Main Authors: Chai, Sam, Wan, Xiaoping, Nassal, Drew M., Liu, Haiyan, Moravec, Christine S., Ramirez-Navarro, Angelina, Deschênes, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495933/
https://ncbi.nlm.nih.gov/pubmed/28341634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00107.2017
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