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Reduced membrane cholesterol limits pulmonary endothelial Ca(2+) entry after chronic hypoxia
Chronic hypoxia (CH)-induced pulmonary hypertension is associated with diminished production of endothelium-derived Ca(2+)-dependent vasodilators such as nitric oxide. Interestingly, ATP-induced endothelial Ca(2+) entry as well as membrane cholesterol (Chol) are decreased in pulmonary arteries from...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495930/ https://ncbi.nlm.nih.gov/pubmed/28364016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00097.2017 |
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