An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury

Acute kidney injury (AKI) causes severe morbidity, mortality, and chronic kidney disease (CKD). Mortality is particularly marked in the elderly and with preexisting CKD. Oxidative stress is a common theme in models of AKI induced by ischemia-reperfusion (I-R) injury. We recently characterized an int...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Ceron, Carla S., Baligand, Celine, Joshi, Sunil, Wanga, Shaynah, Cowley, Patrick M., Walker, Joy P., Song, Sang Heon, Mahimkar, Rajeev, Baker, Anthony J., Raffai, Robert L., Wang, Zhen J., Lovett, David H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495883/
https://ncbi.nlm.nih.gov/pubmed/28331061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00461.2016
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