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Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis
PURPOSE: The extent to which efficacy of the HER2 antibody Trastuzumab in brain metastases is limited by access of antibody to brain lesions remains a question of significant clinical importance. We investigated the uptake and distribution of trastuzumab in brain and mammary fat pad grafts of HER2-p...
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| Publicado no: | Breast Cancer Res Treat |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495871/ https://ncbi.nlm.nih.gov/pubmed/28493046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4279-4 |
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