Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells

Early phase clinical trials evaluating CD8+ T cell-eliciting, HER2-derived peptide vaccines administered to HER2-positive breast cancer patients in the adjuvant setting suggest synergy between the vaccines and trastuzumab, the monoclonal antibody targeting the HER2 protein. Among 60 patients enrolle...

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I publikationen:Cancer Res
Huvudupphovsmän: Gall, Victor A., Philips, Anne V., Qiao, Na, Clise-Dwyer, Karen, Perakis, Alexander A., Zhang, Mao, Clifton, Guy T., Sukhumalchandra, Pariya, Ma, Qing, Reddy, Sangeetha M., Yu, Dihua, Molldrem, Jeffrey J., Peoples, George E., Alatrash, Gheath, Mittendorf, Elizabeth A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626640/
https://ncbi.nlm.nih.gov/pubmed/28819024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2774
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