Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats

Activation of the angiotensin II type 2 receptor (AT2R) by administration of Compound 21 (C21), a selective AT2R agonist, induces neuroprotection in models of ischemic stroke in young adult animals. The mechanisms of this neuroprotective action are varied, and may include direct and indirect effects...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Bennion, Douglas M., Isenberg, Jacob D., Harmel, Allison T., DeMars, Kelly, Dang, Alex N., Jones, Chad H., Pignataro, Megan E., Graham, Justin T., Steckelings, U. Muscha, Alexander, Jon C., Febo, Marcelo, Krause, Eric G., de Kloet, Annette D., Candelario-Jalil, Eduardo, Sumners, Colin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495490/
https://ncbi.nlm.nih.gov/pubmed/28671997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180738
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