APOE ε4-TOMM40 ‘523 haplotypes and the risk of Alzheimer’s disease in older Caucasian and African Americans

Patterns of linkage between the ε4 allele of Apolipoprotein E (APOE) and ‘523 poly-T alleles in the adjacent gene, TOMM40, differ between Caucasian and African Americans. The extent to which this difference affects the risk of Alzheimer’s disease (AD) is unclear. We compared the APOE ε4-TOMM40 ‘523...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Yu, Lei, Lutz, Michael W., Wilson, Robert S., Burns, Daniel K., Roses, Allen D., Saunders, Ann M., Yang, Jingyun, Gaiteri, Chris, De Jager, Philip L., Barnes, Lisa L., Bennett, David A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495438/
https://ncbi.nlm.nih.gov/pubmed/28672022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180356
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