APOE ε4-TOMM40 ‘523 haplotypes and the risk of Alzheimer’s disease in older Caucasian and African Americans

Patterns of linkage between the ε4 allele of Apolipoprotein E (APOE) and ‘523 poly-T alleles in the adjacent gene, TOMM40, differ between Caucasian and African Americans. The extent to which this difference affects the risk of Alzheimer’s disease (AD) is unclear. We compared the APOE ε4-TOMM40 ‘523...

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Pubblicato in:PLoS One
Autori principali: Yu, Lei, Lutz, Michael W., Wilson, Robert S., Burns, Daniel K., Roses, Allen D., Saunders, Ann M., Yang, Jingyun, Gaiteri, Chris, De Jager, Philip L., Barnes, Lisa L., Bennett, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495438/
https://ncbi.nlm.nih.gov/pubmed/28672022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180356
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