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Simultaneous inhibition of aryl hydrocarbon receptor (AhR) and Src abolishes androgen receptor signaling

Altered c-Src activity has been strongly implicated in the development, growth, progression, and metastasis of human cancers including prostate cancer. Src is known to regulate several biological functions of tumor cells, including proliferation. There are several Src inhibitors under evaluation for...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Ghotbaddini, Maryam, Cisse, Keyana, Carey, Alexis, Powell, Joann B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495210/
https://ncbi.nlm.nih.gov/pubmed/28671964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179844
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