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Simultaneous inhibition of aryl hydrocarbon receptor (AhR) and Src abolishes androgen receptor signaling

Altered c-Src activity has been strongly implicated in the development, growth, progression, and metastasis of human cancers including prostate cancer. Src is known to regulate several biological functions of tumor cells, including proliferation. There are several Src inhibitors under evaluation for...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ghotbaddini, Maryam, Cisse, Keyana, Carey, Alexis, Powell, Joann B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495210/
https://ncbi.nlm.nih.gov/pubmed/28671964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179844
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