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Simultaneous inhibition of aryl hydrocarbon receptor (AhR) and Src abolishes androgen receptor signaling

Altered c-Src activity has been strongly implicated in the development, growth, progression, and metastasis of human cancers including prostate cancer. Src is known to regulate several biological functions of tumor cells, including proliferation. There are several Src inhibitors under evaluation for...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Ghotbaddini, Maryam, Cisse, Keyana, Carey, Alexis, Powell, Joann B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495210/
https://ncbi.nlm.nih.gov/pubmed/28671964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179844
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