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The AhR Ligand, TCDD, Regulates Androgen Receptor Activity Differently in Androgen-Sensitive versus Castration-Resistant Human Prostate Cancer Cells

The reported biological effects of TCDD include induction of drug metabolizing enzymes, wasting syndrome and tumor promotion. TCDD elicits most of its effects through binding the aryl hydrocarbon receptor (AhR). TCDD induced degradation of AhR has been widely reported and requires ubiquitination of...

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Bibliografische gegevens
Gepubliceerd in:Int J Environ Res Public Health
Hoofdauteurs: Ghotbaddini, Maryam, Powell, Joann B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515671/
https://ncbi.nlm.nih.gov/pubmed/26154658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph120707506
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