The HBV RNA pre-genome encodes specific motifs that mediate interactions with the viral core protein that promote nucleocapsid assembly

Formation of the Hepatitis B (HBV) nucleocapsid (NC) is an essential step in the viral lifecycle but its assembly is not fully understood. We report the discovery of sequence-specific interactions between the viral pre-genome and HBV core protein (Cp) that play roles in defining the NC assembly path...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Microbiol
Autori principali: Patel, Nikesh, White, Simon J., Thompson, Rebecca F, Bingham, Richard, Weiß, Eva U., Maskell, Daniel P., Zlotnick, Adam, Dykeman, Eric, Tuma, Roman, Twarock, Reidun, Ranson, Neil A., Stockley, Peter G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495169/
https://ncbi.nlm.nih.gov/pubmed/28628133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.98
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi