The HBV RNA pre-genome encodes specific motifs that mediate interactions with the viral core protein that promote nucleocapsid assembly

Formation of the Hepatitis B (HBV) nucleocapsid (NC) is an essential step in the viral lifecycle but its assembly is not fully understood. We report the discovery of sequence-specific interactions between the viral pre-genome and HBV core protein (Cp) that play roles in defining the NC assembly path...

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Gepubliceerd in:Nat Microbiol
Hoofdauteurs: Patel, Nikesh, White, Simon J., Thompson, Rebecca F, Bingham, Richard, Weiß, Eva U., Maskell, Daniel P., Zlotnick, Adam, Dykeman, Eric, Tuma, Roman, Twarock, Reidun, Ranson, Neil A., Stockley, Peter G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495169/
https://ncbi.nlm.nih.gov/pubmed/28628133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.98
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