Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands

RNA sequences/motifs dispersed across the genome of Hepatitis B Virus regulate formation of nucleocapsid-like particles (NCPs) by core protein (Cp) in vitro, in an epsilon/polymerase-independent fashion. These multiple RNA Packaging Signals (PSs) can each form stem-loops encompassing a Cp-recognitio...

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Publicat a:J Mol Biol
Autors principals: Patel, Nikesh, Abulwerdi, Fardokht, Fatehi, Farzad, Manfield, Iain W., Le Grice, Stuart, Schneekloth, John S., Twarock, Reidun, Stockley, Peter G.
Format: Artigo
Idioma:Inglês
Publicat: 2022
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612645/
https://ncbi.nlm.nih.gov/pubmed/35341740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2022.167557
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