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Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes

Changes in chromatin state play important roles in cell fate transitions. Current computational approaches to analyze chromatin modifications across multiple cell types do not model how the cell types are related on a lineage or over time. To overcome this limitation, we developed a method called Ch...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Roy, Sushmita, Sridharan, Rupa
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495076/
https://ncbi.nlm.nih.gov/pubmed/28424352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.215004.116
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