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Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes

Changes in chromatin state play important roles in cell fate transitions. Current computational approaches to analyze chromatin modifications across multiple cell types do not model how the cell types are related on a lineage or over time. To overcome this limitation, we developed a method called Ch...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Roy, Sushmita, Sridharan, Rupa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495076/
https://ncbi.nlm.nih.gov/pubmed/28424352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.215004.116
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